发明名称 COMBINATION/ASSOCIATION OF ADAPALENE AND BENXOYL PEROXIDE FOR TREATING ACNE LESIONS
摘要 Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
申请公布号 US2014296340(A1) 申请公布日期 2014.10.02
申请号 US201414301816 申请日期 2014.06.11
申请人 GALDERMA RESERCH & DEVELOPMENT 发明人 VERNET Marie-Line Abou Chacra;GROSS Denis;LOESCHE Christian;PONCET Michel
分类号 A61K31/327;A61K31/192 主分类号 A61K31/327
代理机构 代理人
主权项 1. A regimen for the therapeutic treatment of acne lesions, the regimen comprising topically applying to the skin of a subject in need of said treatment, as active ingredients, 0.1% to 0.3% adapalene and 2.5% benzoyl peroxide, combined at fixed doses in a single formula that delivers said active ingredients together synergistically to achieve, in a group of such subjects, a degree of success of at least about 20%, wherein said single formula is applied once daily for a period of 12 weeks.
地址 Biot FR