| 发明名称 |
INTRAVASCULAR DELIVERY OF NANOPARTICLE COMPOSITIONS AND USES THEREOF |
| 摘要 |
The present invention provides methods of delivering a composition comprising nanoparticles that comprise a macrolide and an albumin by directly injecting the nanoparticle composition into the blood vessel wall or the tissue surrounding the blood vessel wall. The methods can be used for inhibiting negative remodeling or vascular fibrosis in the blood vessel and are useful for treating various diseases. |
| 申请公布号 |
US2014296279(A1) |
申请公布日期 |
2014.10.02 |
| 申请号 |
US201214113568 |
申请日期 |
2012.04.27 |
| 申请人 |
Seward Kirk;Desai Neil P. |
发明人 |
Seward Kirk;Desai Neil P. |
| 分类号 |
A61K31/436;A61K9/00;A61M25/00;A61K47/48 |
主分类号 |
A61K31/436 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1: A method of inhibiting negative remodeling in a blood vessel in an individual in need thereof, comprising injecting into the blood vessel wall or tissue surrounding the blood vessel wall an effective amount of a composition comprising nanoparticles comprising a macrolide and an albumin. |
| 地址 |
Dublin CA US |
