发明名称 2-HALO-5-ALKYNYL-PYRIDYL NICOTINIC LIGANDS
摘要 Disclosed are heterocyclic compounds that are ligands for nicotinic acetylcholine receptors. The compounds are useful for treating a mammal suffering from any one of a range of therapeutic indications, including Alzheimer's disease, Parkinson's disease, dyskinesias, Tourette's syndrome, schizophrenia, attention deficit disorder, anxiety, pain, depression, obsessive compulsive disorder, chemical substance abuse, alcoholism, memory deficit, pseudodementia, Ganser's syndrome, migraine pain, bulimia, obesity, premenstrual syndrome or late luteal phase syndrome, tobacco abuse, post-traumatic syndrome, social phobia, chronic fatigue syndrome, premature ejaculation, erectile difficulty, anorexia nervosa, disorders of sleep, autism, mutism, trichotillomania, and hypothermia.
申请公布号 CA2944179(A1) 申请公布日期 2014.10.02
申请号 CA20142944179 申请日期 2014.03.26
申请人 GEORGETOWN UNIVERSITY 发明人 XIAO, YINGXIAN;KELLAR, KENNETH J.;BROWN, MILTON L.;PAIGE, MIKELL A.;LIU, YONG
分类号 A61K31/44;A61K31/397;C07D205/02 主分类号 A61K31/44
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