发明名称 NOREPINEPHRINE AND SELECTIVE SEROTONIN RECEPTOR BLOCKER AND USE THEREOF
摘要 The present invention relates to a norepinephrine and selective serotonin receptor blocker and the use thereof. The norepinephrine and selective serotonin receptor blocker is a compound of formula I, or isomers, pharmaceutically acceptable salts or solvates thereof, wherein R1 is selected from the group consisting of C1-6 alkyl, C1-6 alkoxy, C6-10 aralkyl, C6-10 arylalkoxy, C1-6 haloalkyl and C1-6 haloalkoxy; and R2 is one or more groups each independently selected from the group consisting of hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, nitro, cyano, amino, hydroxyl, C1-6 haloalkyl, and C1-6 haloalkoxy. R3 is one or more groups each independently selected from the group consisting of hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, nitro, cyano, amino, hydroxyl, C1-6 haloalkyl, and C1-6 haloalkoxy. The compound of the present invention is effective norepinephrine and selective serotonin receptor blocker.
申请公布号 EP2784077(A1) 申请公布日期 2014.10.01
申请号 EP20120850909 申请日期 2012.11.21
申请人 BEIJING MEDISAN TECHNOLOGY CO. LTD. 发明人 WANG, MINGXIN;LIU, JINAI;YANG, FAN;WANG, AILING;SUN, JIGUO;WANG, YAN;CUI, JIN;JI, LEI
分类号 C07D491/147;A61K31/437;A61P25/24 主分类号 C07D491/147
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