发明名称 TREATMENT OF RNASE H1 RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO RNASE H1
摘要 The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of RNase H1, in particular, by targeting natural antisense polynucleotides of RNase H1. The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of RNASE H1.
申请公布号 EP2529015(A4) 申请公布日期 2014.10.01
申请号 EP20110735332 申请日期 2011.01.25
申请人 CURNA, INC. 发明人 COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA
分类号 C12N15/113;A61K31/7088;A61K48/00;C12N9/22;C12N15/63 主分类号 C12N15/113
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