| 发明名称 | Low dose methods for treating disorders in which TNFα activity is detrimental | ||
| 摘要 | A method of treating TNFα disorders is described, wherein the method comprises administering a low dose amount of a TNFα inhibitor. | ||
| 申请公布号 | US8846046(B2) | 申请公布日期 | 2014.09.30 |
| 申请号 | US200310693233 | 申请日期 | 2003.10.24 |
| 申请人 | AbbVie Biotechnology Ltd. | 发明人 | Kaymakcalan Zehra;Kamen Robert |
| 分类号 | A61K39/395;C07K16/24;A61K39/00;A61K38/17 | 主分类号 | A61K39/395 |
| 代理机构 | McCarter & English, LLP | 代理人 | McCarter & English, LLP ;Cowles Cristin H. |
| 主权项 | 1. A method for treating arthritis comprising administering by injection to a subject an isolated fully human anti-TNFα antibody at a weekly dose of 0.1 mg/kg such that the arthritis is treated as demonstrable by mean arthritic score, wherein the anti-TNFα antibody is D2E7. | ||
| 地址 | Hamilton BM | ||