发明名称 |
Lepidopteran insect N-acetylglucosaminidase genes and their use in glycoengineering |
摘要 |
A transgenic insect cell line for production of elevated levels of recombinant glycoproteins comprising mammalian-like N-glycans is provided. Also disclosed are nucleic acid sequences encoding β-N-acetylglucosaminidases. |
申请公布号 |
US8846886(B2) |
申请公布日期 |
2014.09.30 |
申请号 |
US200812746808 |
申请日期 |
2008.12.12 |
申请人 |
University of Wyoming |
发明人 |
Jarvis Donald L.;Geisler Christoph |
分类号 |
C07H21/04;C12N9/00;C12N9/10;C12N5/07;C12N5/00;C12N5/10;C12N15/00;C12P21/00;C12N9/24 |
主分类号 |
C07H21/04 |
代理机构 |
Dann, Dorfman, Herrell and Skillman, P.C. |
代理人 |
Hagan Patrick J.;Dann, Dorfman, Herrell and Skillman, P.C. |
主权项 |
1. A cDNA encoding an β-N-acetylglucosaminidase having a sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO:4, SEQ ID NO:6 and SEQ ID NO:8. |
地址 |
Laramie WY US |