USE OF IGF-1 IN THE MODULATION OF TREG CELL ACTIVITY AND THE TREATMENT AND PREVENTION OF AUTOIMMUNE DISORDERS OR DISEASES

摘要

The present invention relates to the use of the Insulin-like growth factor-I (IGF-1) in immune modulation and/or in the treatment or prevention of pathogenic or aberrant immune responses or disorders and/or for use in the treatment or prevention of T-cell mediated disorders or diseases and/or for use in the treatment or prevention of diseases where the immune system contributes to the disease state.

主权项

1. A method for treatment or prevention of pathogenic or aberrant immune responses or disorders and/or for treatment or prevention of T-cell mediated disorders or diseases and/or for treatment or prevention of diseases where the immune system contributes to the disease state and/or for immune modulation, wherein IGF-1 or a vector expressing IGF 1 is administered to a subject in an amount sufficient to modulate the immune response or to treat or prevent said disorders or diseases.