摘要 |
<p>PROBLEM TO BE SOLVED: To provide compounds useful as a protein kinase inhibitor and their pharmaceutical compositions.SOLUTION: Compounds of formula (1), their medically permissible salts and pharmaceutical compositions containing them are provided. In the formula, Ris a haloalkyl group having 1-6 F; Ris alkyl optionally substituted with halo, amino or hydroxyl, etc.; and any adjacent Rgroups may form a substituted 5- to 8-membered carbocyclic, heterocyclic, aryl or heteroaryl ring.</p> |