| 摘要 |
PROBLEM TO BE SOLVED: To provide a medicinal agent which is useful for prevention or treatment of prostate cancer and is safe and stable.SOLUTION: A novel PI polyamide is obtained, which can recognize a base sequence that exists in a transcription regulatory domain (an AR responsive domain) in ACSL3 gene and is specific to an Oct1 gene binding sequence capable of regulating the transcriptional activity of AR and can bind to the base sequence. Thus, also provided are an ACSL3 gene expression inhibitor and a prophylactic and/or therapeutic agent for prostate cancer, each of which contains the PI polyamide as an active ingredient. |
