发明名称 |
A PHARMACEUTICAL COMPOSITION FOR TREATING CANCER, COMPRISING INTERFERON ALPHA CONJUGATE. |
摘要 |
<p>The present invention relates to an anti-cancer pharmaceutical composition comprising an interferon alpha or a polymer congugate thereof and use thereof in the treatment of cancer by co-administration with anti-cancer agents. The interferon alpha conjugate of the present invention shows a longer in vivo half-life and a more excellent anti-cancer activity than the conventional interferon alpha, and in particular, its co-administration with an anti-cancer agent such as gemcitabine has synergistic inhibitory effects on cancer cell growth and proliferation so as to exhibit a remarkably excellent anti-cancer activity. Further, the anti-cancer pharmaceutical composition of the present invention has excellent in vivo half-life and anti-cancer activity to greatly reduce administration frequency. Co-administration of an anti-cancer agent and the interferon alpha conjugate having excellent anti-cancer activity reduces administration dose of anti-cancer agent so as to reduce side effects of anti-cancer agent and increase treatment compliance of patient.</p> |
申请公布号 |
MX2014002555(A) |
申请公布日期 |
2014.09.22 |
申请号 |
MX20140002555 |
申请日期 |
2012.09.05 |
申请人 |
HANMI SCIENCE CO., LTD. |
发明人 |
KWON, SE CHANG;JUNG, SUNG YOUB;CHOI, IN YOUNG;WOOD, YOUNG EUN;LIM, SE YOUNG;LEE, JAE HO;MOON, SUNG HWAN;LIU, JIAWANG |
分类号 |
A61K38/21;A61K39/395;A61K47/30;A61K47/48;A61P35/00 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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