发明名称 ADULT CARDIAC STEM CELL POPULATION
摘要 The present invention relates to the identification, isolation, expansion and characterization of a specific type of adult cardiac stem cell. These adult stem cells are characterised in that they naturally express a specific pattern of markers, which can be used to assist with their isolation and expansion. The cells of the invention display an unprecedented capacity for providing, activating and/or inducing repair of damaged cardiac tissue. These adult stem cells may be used as therapeutic agents including, without limitation, for the regeneration of tissue, particularly for regeneration of damaged cardiac tissue, such as myocardium.
申请公布号 US2014271575(A1) 申请公布日期 2014.09.18
申请号 US201414213868 申请日期 2014.03.14
申请人 CORETHERAPIX SLU 发明人 RODRIGUEZ-BORLADO Luis;PALACIOS Itziar;ABAD José Luis;SÁNCHEZ Belén;ÁLVAREZ Virginia;ROSADO Rosalba
分类号 C12N5/077 主分类号 C12N5/077
代理机构 代理人
主权项 1. A substantially pure population of adult cardiac stem cells, wherein said population of cells expresses the following markers: (a) SOX17 and GATA4 and wherein said population does not express the following markers: (b) Oct4, Nanog and c-kit.
地址 Madrid ES