| 摘要 |
PROBLEM TO BE SOLVED: To provide methods and compositions with improved drug delivery, particularly for antibody-based therapeutics in treating or preventing pulmonary diseases.SOLUTION: The present invention relates to methods and compositions employing an antibody that inhibits activation of the complement system and capable of being used to prevent or treat a pulmonary disease or condition. Pulmonary diseases or conditions contemplated by the application include, but are not limited to, asthma, bronchial constriction, bronchitis, a chronic obstructive pulmonary disease (COPD), interstitial lung diseases, lung malignancies,α-1 anti-trypsin deficiency, emphysema, bronchiectasis, bronchiolitis obliterans, sarcoidosis, pulmonary fibrosis, and collagen vascular disorders. |
