摘要 |
The invention relates to a mutated polypeptide, to strains containing same, and to methods for simultaneously detecting metal cations, for example Au, Cu, Ag, Hg, Pb, Cd, Co and Zn, in samples, wherein the polypeptide comprises a substitution of serine by cisteine in position 77 of SEQ ID N° 1 or SEQ ID N° 2; and wherein said protein has transcriptional regulatory activity, for example GolS or CueR. The polypeptide detects the metals as monovalent and divalent metal cations. |
申请人 |
CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS YTECNICAS (CONICET);UNIVERSIDAD NACIONAL DE ROSARIO;INIS BIOTECH LLC |
发明人 |
IBAÑEZ, MARÍA MARTA;CERMINATI, SEBASTIÁN;CHECA, SUSANA KARINA;SONCINI, FERNANDO CARLOS |