发明名称 |
TRANSPORTER WITH A GLUCOSE SENSOR FOR DETERMINING VIABILITY OF AN ORGAN OR TISSUE |
摘要 |
<p>An apparatus for perfusing an organ or tissue includes a perfusion circuit and a glucose sensor operatively connected to the perfusion circuit. The glucose sensor is configured to detect a target agent that is an indicator of viability of the organ or tissue. The target agent may be Kidney Injury Molecule-1 (KIM-1). The sensor includes a solid support, such as a bead or membrane, to which is attached a recognition molecule that specifically binds to the target agent but not significantly to other agents. The sensor also includes an enzyme that can catalyze the conversion of a substance to glucose. In the presence of the target agent the enzyme can convert the substance into glucose, which can then be detected and optionally be quantified by the sensor.</p> |
申请公布号 |
WO2014143849(A1) |
申请公布日期 |
2014.09.18 |
申请号 |
WO2014US27998 |
申请日期 |
2014.03.14 |
申请人 |
LIFELINE SCIENTIFIC, INC. |
发明人 |
MAYER, STEVEN L.;KRAVITZ, DAVID C.;MAYER, TRACY H. |
分类号 |
A01N1/02 |
主分类号 |
A01N1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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