Disclosed are methods of treating or modulating cachexia and/or increasing lean body mass and/or increasing lower extremity muscle size in a prostate cancer patient comprising administering a therapeutically effective amount of a myostatin antagonist. Further disclosed is the peptibody sequence of the myostatin antagonist, and the formulation of the peptibody.
申请公布号
WO2014144903(A1)
申请公布日期
2014.09.18
申请号
WO2014US29502
申请日期
2014.03.14
申请人
AMGEN INC.;PINTA BIOTHERAPEUTICS, INC.
发明人
PADHI, DESMOND;HAN, HUIQUAN;HAQQ, CHRISTOPHER, MICHAEL;CIECHANOVER, ISAAC