| 发明名称 | Thermogelling anaesthetic compositions | ||
| 摘要 | The present invention relates to a thermogelling pharmaceutical composition comprising local anaesthetics in base form and which is suitable for topical administration. The compositions further comprise a polyoxyethylene castor oil and one or more surfactants to obtain thermogelling characteristics. | ||
| 申请公布号 | US8834927(B2) | 申请公布日期 | 2014.09.16 |
| 申请号 | US201113638511 | 申请日期 | 2011.03.31 |
| 申请人 | Pharmanest AB | 发明人 | Sundberg Mark;Brodin Arne;Kållberg Nils |
| 分类号 | A61K9/00;A61K47/32;A61K47/44;A61K47/10;A61L15/44;A61K9/06 | 主分类号 | A61K9/00 |
| 代理机构 | LeClairRyan, a Professional Corporation | 代理人 | LeClairRyan, a Professional Corporation |
| 主权项 | 1. A pharmaceutical composition comprising: (a) 1 to 10% by weight of lidocaine in base form, which is solubilized in 10 to 30% by weight of a polyoxyethylene castor oil; (b) 15 to 30% by weight of one or more non-ionic block copolymers of poly(oxyethylene) and poly(oxypropylene) type; and (c) water, wherein the pH of the composition is at least the value of the pKa of said lidocaine. | ||
| 地址 | Solna SE | ||