| 发明名称 | Natriuretic polypeptide delivery systems | ||
| 摘要 | This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided. | ||
| 申请公布号 | US8835601(B2) | 申请公布日期 | 2014.09.16 |
| 申请号 | US201313788309 | 申请日期 | 2013.03.07 |
| 申请人 | Mayo Foundation for Medical Education and Research;Nanyang Technological University | 发明人 | Chen Horng H.;Burnett, Jr. John C.;Ghim Lim Soo;Venkatraman Subramanian S. |
| 分类号 | A61K38/00;A61K47/34 | 主分类号 | A61K38/00 |
| 代理机构 | Fish & Richardson P.C. | 代理人 | Fish & Richardson P.C. |
| 主权项 | 1. A polymer gel composition comprising a natriuretic polypeptide, poly(lactic-co-glycolic acid), N-methyl-2-pyrrolidinone, and triacetin, wherein the poly(lactic-co-glycolic acid) of said composition has an intrinsic viscosity between 0.3 and 3 dL/g, and wherein said natriuretic polypeptide is released from said gel composition into a mammal's circulation over a period of time greater than 4 weeks, when said gel composition is delivered to said mammal. | ||
| 地址 | Rochester MN US | ||