| 发明名称 |
PHARMACEUTICAL COMPOSITION OF OMEPRAZOLE |
| 摘要 |
The present invention refers to oral solid pharmaceutical compositions comprising concentrate omeprazole pellets, processes for the preparation of the same and their use as medicaments, more particularly for the treatment and/or prophylaxis of a gastrointestinal disorder. |
| 申请公布号 |
US2014255503(A1) |
申请公布日期 |
2014.09.11 |
| 申请号 |
US201214350901 |
申请日期 |
2012.10.31 |
| 申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
Sangrà Perez Jaume;Alcocer Aranzana Cristina |
| 分类号 |
A61K9/50;A61K31/4439 |
主分类号 |
A61K9/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pellet comprising:
a) a core comprising omeprazole or a pharmaceutically acceptable salt thereof; b) at least an intermediate layer; and c) an enteric coating layer comprising an enteric polymer; and characterized in that the weight percentage of the enteric coating layer is between 5% (w/w) and 40% (w/w) with respect to the total weight of the pellet and wherein the core (a) comprises an inert nucleus having a diameter average size lying between about 0.3 mm and 0.9 mm. |
| 地址 |
Barcelona ES |
