| 摘要 |
FIELD: medicine.SUBSTANCE: carbon nanostructure surface is modified with (2,4,5-triiodophenyl)-methanol; the modified carbon nanostructures are analysed to measure a iodine amount; the prepared modified carbon nanostructures are administered into an experimental animal's body to take organs and tissues thereafter, to homogenise them in a 0.5-2 M NaOH solution, to sample a homogenate, to dilute with water, to expose the diluted sample to ultrasound to a temperature of 40-70°C, to determine a iodine amount in the prepared sample by mass spectrometry with inductively bound plasma and to calculate the carbon nanostructure content in the sample as shown by a difference of the iodine amount in the sample prior to administration of the modified carbon nanostructures and after administration thereof into the body and to re-calculate this iodine amount into the carbon nanostructure content in the sample with the use of the initial iodine content in the modified carbon nanostructure.EFFECT: method provides monitoring in vivo of the carbon nanostructure distribution in the body.2 cl, 6 dwg, 3 ex, 2 tbl |
