ASSAY FOR POLYPEPTIDE AGGREGATION USING MICRODROPLETS

摘要

A method for detecting the presence of aggregatory seeds of a polypeptide in a sample is provided. The method may be used for identifying a subject at risk of a conformational disease caused by the aggregation of a polypeptide or for diagnosing, assessing or monitoring a conformational disease caused by the aggregation of a polypeptide in a subject. The invention also relates to methods for preparing a product free from aggregatory seeds of a polypeptide and methods for measuring the effect of a test substance on the aggregation of a polypeptide.