发明名称 BISPECIFIC T CELL ACTIVATING ANTIGEN BINDING MOLECULES
摘要 The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
申请公布号 CA2896370(A1) 申请公布日期 2014.09.04
申请号 CA20142896370 申请日期 2014.02.21
申请人 ROCHE GLYCART AG 发明人 BACAC, MARINA;BRUENKER, PETER;JAEGER, CHRISTIANE;KLEIN, CHRISTIAN;MOESSNER, EKKEHARD;UMANA, PABLO;WEINZIERL, TINA
分类号 C07K16/30;A61P35/00;C07K16/28;C07K16/32;C07K16/46 主分类号 C07K16/30
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