PLASTID-EXPRESSED MYCOBACTERIUM TUBERCULOSIS VACCINE ANTIGENS ESAT-6 AND MTB72F FUSED TO CHOLERA TOXIN B SUBUNIT

摘要

Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the leading reasons for death by an infectious bacterial pathogen. Disclosed herein are compositions and methods of using same related to chloroplast expressed TB antigens. Also disclosed is the bioencapsulation of the TB antigens that enables the oral administration of the composition while preserving immunizing efficacy.