发明名称 |
DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS |
摘要 |
Disclosed are novel dipeptide analogs compounds of Formula (I), (II) or (III): or a stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, or a prodrug thereof, which are inhibitors of factor XIa and/or plasma kallikrein, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of thrombotic diseases. |
申请公布号 |
EP2152664(B1) |
申请公布日期 |
2014.09.03 |
申请号 |
EP20080770664 |
申请日期 |
2008.06.11 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PINTO, DONALD J. P.;QUAN, MIMI L.;SMITH II, LEON M.;ORWAT, MICHAEL J.;GILLIGAN, PAUL J. |
分类号 |
C07C237/22;A61K31/41;C07D231/56;C07D249/06;C07D257/04;C07D401/12;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D498/04 |
主分类号 |
C07C237/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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