| 发明名称 |
Alkynyl derivatives as modulators of metabotropic glutamate receptors |
| 摘要 |
<p>The present invention relates to novel compounds of formula I wherein W, n, X and W' are defined in the description; invention compounds are modulators of metabotropic glutamate receptors - subtype 5 ("mGluR5") which are useful for the treatment of central nervous system disorders as well as other disorders modulated by mGluR5 receptors.
<Chemistry id="chema01" num="0001"><Image id="ia01" he="21" wi="81" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" /></Chemistry></p> |
| 申请公布号 |
EP2426115(A3) |
申请公布日期 |
2014.09.03 |
| 申请号 |
EP20110186934 |
申请日期 |
2005.06.17 |
| 申请人 |
ADDEX PHARMA SA |
发明人 |
BESSIS, ANNE-SOPHIE;BOLEA, CHRISTELLE;BONNET, BEATRICE;EPPING-JORDAN, MARK;POIRIER, NICHOLAS;POLI, SONIA-MARIA;ROCHER, JEAN-PHILIPPE;THOLLON, YVES |
| 分类号 |
C07D277/22;A61K31/4035;A61K31/4196;A61K31/422;A61K31/423;A61K31/4245;A61K31/427;A61K31/428;A61K31/44;A61K31/4427;A61K31/47;A61K31/4709;A61K31/506;A61P25/28;C07D213/56;C07D215/06;C07D233/54;C07D233/56;C07D239/26;C07D263/56;C07D401/06;C07D403/06;C07D413/06;C07D417/06;C07D471/04;C07D498/04 |
主分类号 |
C07D277/22 |
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