COMPOSTO, COMPOSIÇÃO FARMACÊUTICA, MÉTODOS PARA O TRATAMENTO DE UMA DOENÇA OU DISTÚRBIO, E PARA MODULAR A ATIVIDADE DE BACE

摘要

The present invention provides a 2-amino-5-[substituted-4-(difluoromethoxy)phenyl]-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit beta-secretase (BACE) and treat beta-amyloid deposits and neurofibrillary tangles.