发明名称 REAGENT BASED ON GOLD NANO PARTICLES, PROCESS FOR PREPARING THE SAME AND USE THEREOF FOR MAPPING TUMOUR TISSUE ARCHITECTURE
摘要 <p>The invention relates to a process for tissue mapping with a view to determining tumour limits, both at the surface and in depth, while also pointing out tumour cell nests in the vicinity of the tumour. According to the invention, the process is based on plasmon resonance at the surface of gold nano particles placed in a dielectric medium with high refraction index, the said nano particles entering the tumour through arterioles and capillaries, the interstitial space and the cells and remain fixed in the tissue, and, upon performing a UV-spectrum assay, they emit a highly fluorescent light thus generating a particular tissue and tumour cells appearance.</p>
申请公布号 RO128557(B1) 申请公布日期 2014.08.29
申请号 RO20110001255 申请日期 2011.11.28
申请人 INSTITUTUL NA&Tcedil,IONAL DE CERCETARE-DEZVOLTARE PENTRU MICROTEHNOLOGIE 发明人 AVRAM MARIOARA;PETRESCU INA RUXANDRA;AVRAM MARIUS ANDREI;R&Abreve,DOI ANTONIO MARIAN
分类号 G01N33/52;B82Y5/00 主分类号 G01N33/52
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