发明名称 ORALLY ADMINISTERED ADSORBENT, THERAPEUTIC AGENT FOR RENAL DISEASE, AND THERAPEUTIC AGENT FOR LIVER DISEASE
摘要 The purpose of the present invention is to provide an orally administered adsorbent capable of adsorbing large quantities of tryptophan or indoxyl sulfate in the presence of bile acid. Accordingly, an orally administered adsorbent is characterized by including spherical active carbon which has: a bulk density of 0.30-0.46 g/mL; a specific surface area obtained using the Brunauer-Emmett-Teller (BET) method of at least 2000 m2/g; a total acid group content of less than 0.30 meq/g; a volume of pores having diameters in the range 20-10000 nm of not more than 0.21 mL/g; and a micropore volume ratio (Vm) of at least 1.0, said micropore volume ratio (Vm) being obtained using formula (1), namely Vm = (V2.0-V1.1)/(V1.1-V0.64) (in formula (1), V2.0, V1.1, and V0.64 are the cumulative volumes of pores having diameters of not more than 2.0 nm, not more than 1.1 nm, and not more than 0.64 nm, respectively, said volumes being calculated from nitrogen adsorption amounts using the Saito-Foley (SF) method).
申请公布号 WO2014129614(A1) 申请公布日期 2014.08.28
申请号 WO2014JP54261 申请日期 2014.02.24
申请人 KUREHA CORPORATION 发明人 SONOBE NAOHIRO;WAKAHOI TAKASHI;AKITA TAKAHIRO
分类号 A61K33/44;A61P1/16;A61P13/12;A61P39/02;B01J20/20;C01B31/10 主分类号 A61K33/44
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