发明名称 PENTOSE FERMENTATION BY A RECOMBINANT MICROORGANISM
摘要 The present invention provides recombinant nucleic acid constructs comprising a xylose isomerase polynucleotide, a recombinant fungal host cell comprising a recombinant xylose isomerase polynucleotide, and related methods.
申请公布号 US2014242674(A1) 申请公布日期 2014.08.28
申请号 US201414278348 申请日期 2014.05.15
申请人 Codexis, Inc. 发明人 Subbian Ezhilkani;Grate John H.;Cho Catherine M.;Mijts Benjamin N.;Benoit Jeanne Bonomo
分类号 C12N9/90 主分类号 C12N9/90
代理机构 代理人
主权项 1. A recombinant nucleic acid construct comprising at least one polynucleotide sequence that encodes a polypeptide which is capable of catalyzing the isomerization of D-xylose directly to D-xylulose, wherein the polynucleotide is a polynucleotide that encodes a polypeptide comprising an amino acid sequence having at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, or at least 95% identity to SEQ ID NO:23; 25, 27, 29, 31, and/ or 33, or a polynucleotide that hybridizes under stringent hybridization conditions to the complement of a polynucleotide that encodes a polypeptide having the amino acid sequence of SEQ ID NO: 23; 25, 27, 29, 31, and/ or 33.
地址 Redwood City CA US