| 发明名称 |
Compositions and Methods for Inhibiting Expression of a Gene from the Ebola Virus |
| 摘要 |
The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus. |
| 申请公布号 |
US2014243394(A1) |
申请公布日期 |
2014.08.28 |
| 申请号 |
US201414279156 |
申请日期 |
2014.05.15 |
| 申请人 |
Alnylam Pharmaceuticals Inc. ;The Government of the United States, as Represented by the Secretary of the Army |
发明人 |
Bavari Sina;Warfield Kelly Lyn;Tan Pamela;Borodovsky Anna;Novobrantseva Tatiana;de Fougerolles Antonin |
| 分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a human Ebola genome in a cell, wherein said dsRNA comprises at least two sequences that are complementary to each other and wherein a sense strand comprises a first sequence and an antisense strand comprises a second sequence comprising a region of complementarity which is substantially complementary to at least a part of a mRNA encoding Ebola, and wherein said region of complementarity is less than 30 nucleotides in length. |
| 地址 |
Cambridge MA US |
