发明名称 THERAPEUTIC COMPOSITIONS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY
摘要 Compositions for therapy of a diabetic symmetrical polyneuropathy a subject in need thereof, the compositions comprising: an effective amount of a muscarinic acetylcholine receptor antagonist exemplified by pirenzepine, telenzepine, atropine, or derivatives thereof or salts thereof or analogs thereof or derivatives thereof, and a pharmacologically acceptable carrier. The composition may be injectable or alternatively, may be applied topically or alternatively, may be delivered orally. A suitable topical composition may comprise a lotion, a cream, a gel, or a viscous fluid. The muscarinic acetylcholine receptor antagonist may be a muscarinic acetylcholine receptor antagonist salt or a muscarinic acetylcholine receptor antagonist derivative or a muscarinic acetylcholine receptor antagonist analog.
申请公布号 EP2632468(A4) 申请公布日期 2014.08.27
申请号 EP20110835385 申请日期 2011.10.24
申请人 UNIVERSITY OF MANITOBA 发明人 FERNYHOUGH, PAUL;CALCUTT, NIGEL, A.;KOTRA, LAKSHMI
分类号 A61K31/5513;A61K31/46;A61K31/496;A61P25/02;C07D417/12;C07D451/10;C07D471/04;C07D495/04 主分类号 A61K31/5513
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