| 摘要 |
FIELD: medicine, pharmaceutics.SUBSTANCE: group of inventions refers to pharmaceutics and concerns a solid pharmaceutical product, a solid composition applicable in methods for photodynamic diagnosing of cancer, pre-cancer and non-cancer conditions of the lower gastrointestinal system. The solid pharmaceutical composition and pharmaceutical product contain an active ingredient representing 5-aminolevulinic acid (5-ALA), or 5-ALA ester, or their pharmaceutically acceptable salts, as well as one or more triglycerides and one or more non-ionic emulsifiers and additionally one or more enteric coating. Further, the invention refers to a method for photodynamic diagnosing of cancer, pre-cancer and non-cancer conditions of the lower gastrointestinal tract, wherein the above solid pharmaceutical compositions and pharmaceutical products are applicable.EFFECT: group of inventions provides the effective concentration of 5-ALA in the lower gastrointestinal tract, the homogenous distribution of 5-ALA, ease of use.17 cl, 3 ex, 9 dwg |
