| 发明名称 |
CRYSTALLINE PEPTIDE EPOXY KETONE PROTEASE INHIBITORS AND THE SYNTHESIS OF AMINO ACID KETO~EPOXIDES |
| 摘要 |
<p>The invention relates to crystalline peptide keto epoxide compounds, methods of their preparation, and related pharmaceutical compositions. This invention also relates to methods for the preparation of amino acid keto-epoxides. Specifically, allylic ketones are stereoselectively converted to the desired keto epoxides.</p> |
| 申请公布号 |
PH12013501377(A1) |
申请公布日期 |
2014.08.27 |
| 申请号 |
PH12013501377 |
申请日期 |
2013.06.26 |
| 申请人 |
ONYX THERAPEUTICS, INC. |
发明人 |
PASIT PHIASIVONGSA;LOUIS C. SEHL;WILLIAM DEAN FULLER;GUY J. LAIDIG |
| 分类号 |
A61P19/08;A61P25/28;A61P31/00;A61P33/00;A61P35/00;A61P37/00;A61P37/06;C07D303/36;C07K5/10;C07K5/107 |
主分类号 |
A61P19/08 |
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