| 摘要 |
<p>The present invention relates to a novel crystalline acid addition salt of a tricyclo derivative compound or a hydride thereof, and to a production method therefor. The crystalline acid addition salt or the hydride thereof according to the present invention is stable with respect to moisture and consequently stable with respect to hygroscopicity and so is very useful in maintaining quality when producing a drug, and, in addition, can be used to advantage as a pharmaceutical composition for treating neuropathic pain, epilepsy, stroke, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), Huntington's disease, schizophrenia, chronic and acute pain, ischemic brain injury, neuronal loss after hypoxia, trauma and nerve damage, which are medical conditions induced by PARP (poly (ADP-ribose) polymerase) overactivity.</p> |
