发明名称 SYNERGISTIC MODULATION OF FLT3 KINASE USING A FLT3 INHIBITOR AND A FARNESYL TRANSFERASE INHIBITOR
摘要 The invention is directed to a method of inhibiting FLT3 tyrosine kinase activity or expression or reducing FLT3 kinase activity or expression in a cell or a subject comprising the administration of a farnesyl transferase inhibitor and a FLT3 kinase inhibitor selected from compounds of Formula I': Included within the present invention is both prophylactic and therapeutic methods for treating a subject at risk of (or susceptible to) developing a cell proliferative disorder or a disorder related to FLT3.
申请公布号 KR101433595(B1) 申请公布日期 2014.08.26
申请号 KR20087000608 申请日期 2006.06.07
申请人 发明人
分类号 A61K31/4427;A61P35/00 主分类号 A61K31/4427
代理机构 代理人
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