发明名称 Prolyl hydroxylase inhibitors
摘要 The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I); which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
申请公布号 US8815884(B2) 申请公布日期 2014.08.26
申请号 US201314026164 申请日期 2013.09.13
申请人 GlaxoSmithKline LLC 发明人 Fitch Duke M.;Shaw Antony N.;Wiggall Kenneth
分类号 C07D239/54;A61K31/515 主分类号 C07D239/54
代理机构 代理人 Coulter Kathryn L.;Kanagy James M.
主权项 1. A pharmaceutical composition for oral administration which comprises 1-700 mg of the compound:or a salt thereof and one or more pharmaceutically acceptable carriers, diluents or excipients.
地址 Philadelphia PA US