发明名称 |
Prolyl hydroxylase inhibitors |
摘要 |
The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I);
which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example. |
申请公布号 |
US8815884(B2) |
申请公布日期 |
2014.08.26 |
申请号 |
US201314026164 |
申请日期 |
2013.09.13 |
申请人 |
GlaxoSmithKline LLC |
发明人 |
Fitch Duke M.;Shaw Antony N.;Wiggall Kenneth |
分类号 |
C07D239/54;A61K31/515 |
主分类号 |
C07D239/54 |
代理机构 |
|
代理人 |
Coulter Kathryn L.;Kanagy James M. |
主权项 |
1. A pharmaceutical composition for oral administration which comprises 1-700 mg of the compound:or a salt thereof and one or more pharmaceutically acceptable carriers, diluents or excipients. |
地址 |
Philadelphia PA US |