| 发明名称 |
FORMULATIONS OF THIOPHENE COMPOUNDS |
| 摘要 |
A pharmaceutical composition comprises: a) polymorphic form M or tromethamine salt of Compound (1) represented by the following structural formula:;and b) a filler. A method of preparing a pharmaceutical composition comprises: providing a mixture of Compound (1) and a filler to form the composition of Compound (1). A method of treating a HCV infection in a subject comprises administering to the subject a therapeutically effective amount of the pharmaceutical composition. |
| 申请公布号 |
US2014235705(A1) |
申请公布日期 |
2014.08.21 |
| 申请号 |
US201414163064 |
申请日期 |
2014.01.24 |
| 申请人 |
Vertex Pharmaceuticals Incorporated |
发明人 |
Cardoso Nicholas;Gu Chong-Hui;Ojakovo Peter A.;Sanghvi Tapan;Simone Eric A.;Verwijs Marinus J. |
| 分类号 |
A61K31/381 |
主分类号 |
A61K31/381 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising:
a) polymorphic form M or tromethamine salt of Compound (1) represented by the following structural formula:and
b) a filler. |
| 地址 |
Boston MA US |
