Porous structure with independently controlled surface patterns

摘要

Disclosed herein are systems and methods for manufacturing and using a cell culture support device. The device includes a plurality of polymer layers, each with at least one flow chamber defined therethrough. The device also includes a cross channel interface between the channels of different polymer layers. The cross channel interface includes a plurality of pores and a topographical pattern that is selected independent of the plurality of pores. Furthermore, the formation of the topographical pattern preservers the pores.