METHOD AND APPARATUS FOR MULTI-STATE HEART FAILURE DECOMPENSATION DETECTION

摘要

Devices and methods for detecting events indicative of heart failure (HF) decompensation status are described. An ambulatory medical device can determine the present physiologic state as being either a drift state or a stable state, and applies an algorithm to detect HF decompensation event according to the physiologic state. In some embodiments, the ambulatory medical device uses the present physiologic state to estimate one ore more expected future signal characteristics, and to detect HF decompensation event using the one or more expected futures signal characteristics.

主权项

1. An ambulatory medical device, comprising:
a signal sensing circuit, configured to sense a physiologic signal indicative of the patient's heart failure (HF) decompensation status; a physiologic state analyzer circuit, including at least one of:
a timer or a clock configured to determine a current elapsed time since a physiologic state trigger event;a drift metric calculator circuit, configured to calculate a drift metric using at least one of:
a comparison between (1) first measurements of the physiologic signal obtained during a first time window and (2) second measurements of the physiologic signal obtained during a non-overlapping second time window; ora function of a first or higher order derivative of the physiological signal obtained from two or more non-identical time windows; wherein the physiologic state analyzer circuit is configured to determine a physiologic state of the patient using at least one of the elapsed time or the calculated drift metric; and an HF decompensation event detector circuit, configured to detect an indication of HF decompensation status using the determined physiologic state and the sensed physiologic signal.