CANCER VACCINES AND VACCINATION METHODS

摘要

Compositions of multipeptide vaccines comprising at least seven tumor associated antigens, compositions of antigen presenting cell (e.g., dendritic cell) based vaccines presenting epitopes from at least seven tumor associated antigens, and methods of making same, are provided herein. Also, disclosed are methods for treating gynecological and peritoneal cancers using such vaccines.

主权项

1. A composition comprising a mixture of at least one major histocompatibility complex (MHC) class I peptide epitope of at least seven antigens selected from the group consisting of mesothelin, NY-ESO-1, FBP, HER-2/neu, IL-13 receptor α2, MAGE-A1, EphA2, p53, k-Ras, Ep-CAM, MUC1, Survivin, hTERT, and WT1.