发明名称 |
KIT FOR MEASURING THE THROMBIN GENERATION IN A SAMPLE OF A PATIENT'S BLOOD OR PLASMA |
摘要 |
The invention provides a kit for measuring the thrombin generation in a sample of a patient's blood or plasma, or in a sample of clotting factors. The kit contains lyophilized tissue factor/phospholipid-complex and a lyophilized mixture containing a thrombin-substrate and CaCl2. The invention also provides processes for preparing the reagents for the kit. The kit can be used in a method for measuring the thrombin generation in a sample, wherein it is possible to detect changes in thrombin generation kinetics, for example after administration of inhibitor bypassing agents to a patient who has developed inhibitors to an exogenous clotting factor such as Factor VIII. |
申请公布号 |
US2014232029(A1) |
申请公布日期 |
2014.08.21 |
申请号 |
US201414261608 |
申请日期 |
2014.04.25 |
申请人 |
Baxter International Inc. ;Baxter Healthcare SA |
发明人 |
Varadi Katalin;Turecek Peter;Keil Brigitte;Peyrer-Heimstaett Sylvia;Schwarz Hans-Peter |
分类号 |
A61K31/66 |
主分类号 |
A61K31/66 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
Deerfield IL US |