摘要 |
A liner-based assembly including an overpack, a liner disposed within the overpack, and a filling connector securable to at least one of the overpack and the liner and ineloding a membrane for substantially aseptic filling. The membrane may be an elastomeric stopper, which may be configured, for re-sealing with or without the assistance of heat The liner-based assembly may further include a dispense connector that is operably connected with the overpack and/or the liner. The dispense connector may comprise or be operably connected to a one-way valve, the one-way valve having —an elastomeric portion defining an opening and generally operably coupled with a plug member positioned within the—opening. In a closed position, the elastomeric portion may be sealed against the plug member, and when a pressure is applied against the elastomeric portion, the elastomeric portion may flex in a manner configured —to permit only one—way flow through the opening. |