| 摘要 |
FIELD: chemistry.SUBSTANCE: described is a method of obtaining carbonatehydroxylapatite, approximated to an inorganic matrix of the bone tissue from the model solution of human synovial fluid, in which a model medium of the claimed composition is prepared: CaCl- 1.3431 g/l, NaHPO·12HO - 7.4822 g/l, NaCl - 2.8798 g/l, MgCl?6HO - 0.4764 g/l, NaSO- 1.6188 g/l, KCl - 0.3427 g/l, sedimentation is carried out at the concentration of carbonate-ions 24 mmol/l, a temperature of 22-25°C, pH value of 7.4±0.05 for 30 days. Carbonatehydroxylapatite has unimodal distribution of particles by sizes, with a value of their average diameter for CHA (42.38 mcm). Carbonate-ions are included into the structure of hydroxylapatite in positions of hydroxyl groups (OH), which is proved by data of IR-spectroscopy.EFFECT: synthesis results in carbonatehydroxylapatite of A-type, which is approximated to the inorganic matrix of the bone tissue.2 dwg, 3 tbl |
