摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a peptide represented by the formula (I) X-Leu-X-Leu-X, where Xis Glu or Asp, Xis His, Lys or Arg, Xis Asp or Glu, at that Glu, Asp, Leu, His, Lys and Arg, or its pharmaceutically acceptable salt and its compositions for treatment or prevention of cartilage damage and/or arthritis.EFFECT: proposed peptide can affect the regeneration of cartilage tissue, inhibition of expression of the enzyme causing cartilage tissue matrix degradation, or inhibition of chondrosteosis.7 cl, 2 tbl, 11 dwg, 15 ex |