摘要 |
PROBLEM TO BE SOLVED: To provide a tribonectin and a method of tribosupplementation carried out by administering tribonectins directly to an injured joint or an arthritic joint.SOLUTION: The tribonectin comprises at least one O-linked lubricating moiety which includes a &bgr;(1-3) Gal-GalNAc moiety. The method of tribosupplementation is a method for lubricating a mammalian joint, comprising the step of bringing the joint into contact with an isolated megakaryocyte stimulating factor (MSF) gene product. |