METHOD FOR PRODUCING L-LYSINE BY MODIFYING ACONITASE GENE AND/OR REGULATORY ELEMENTS THEREOF

摘要

Provided is an L-lysine generation method by fermentation, comprising modifying the aconitase gene and/or regulatory element thereof on a bacteria chromosome, such that the enzymatic activity and/or expression quantity of the aconitase are reduced but do not disappear; and generating L-lysine by fermenting the modified bacteria. Also disclosed are methods and uses derived from the present method, and the bacteria that can be used in these methods and uses.