COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING MECHANICALLY-INDUCED SKIN INFLAMMATION

摘要

Compositions for alleviating mechanically-induced skin inflammation, such as that caused by shaving, contain substituted azole. Methods for alleviating mechanically-induced skin inflammation include the step of applying a composition comprising substituted azole to a skin surface subject to mechanically-induced inflammation. In particular embodiments the substituted azole compound is 1-phenylimidazole, 4-phenylimidazole, or a combination thereof. An effective amount of the composition is applied for a period of time sufficient to alleviate mechanically-induced skin inflammation.

主权项

1. A method of alleviating mechanically-induced skin inflammation comprising:
a. identifying a target skin surface subject to mechanically-induced inflammation; b. applying to said skin surface a composition comprising:
i. an effective amount of a substituted azole compound represented by the structure: where:
R1 is an alkyl or phenyl electron donating groupR2 is hydrogenR3 and R4 do not form a fused ring, and each is independently selected from the group consisting of H, alkyl, and phenyl; andii. a dermatologically acceptable carrier;wherein said composition is applied for a period of time sufficient to improve the appearance of one or more signs of mechanically-induced inflammation.