发明名称 |
ANTIMICROBIAL PEPTIDES DERIVED FROM HEPATITIS B VIRUS CORE PROTEIN ARGININE-RICH DOMAIN |
摘要 |
A pharmaceutical composition for use in killing and/or inhibiting the growth and/or proliferation of a microorganism in a subject in need thereof, or for treating a subject afflicted with a microbial infection is disclosed. The composition comprises: (a) an effective amount of an isolated peptide, wherein the peptide comprises the arginine-rich carboxy-terminal region of hepatitis B virus core protein (HBc) and exhibits an antimicrobial activity; and (b) a pharmaceutically acceptable carrier. The peptide exhibits an activity against Gram-negative bacteria, Gram-positive bacteria, and/or fungi. |
申请公布号 |
WO2014124047(A1) |
申请公布日期 |
2014.08.14 |
申请号 |
WO2014US14938 |
申请日期 |
2014.02.05 |
申请人 |
ACADEMIA SINICA;LIANG, CHI-MING |
发明人 |
SHIH, CHIAHO;CHEN, HENG-LI;SU, PEI-YI |
分类号 |
A01N37/18;A61K39/29;A61P31/04 |
主分类号 |
A01N37/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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