| 发明名称 |
HCV Helicase Inhibitors and Methods of Use Thereof |
| 摘要 |
The present invention discloses thioflavine S and primuline derivatives which inhibit hepatitis C virus helicase and protease activity. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are useful as antiviral agents. The present invention further relates to pharmaceutical compositions containing the aforementioned compounds and methods of treating an HCV infection. |
| 申请公布号 |
US2014227225(A1) |
申请公布日期 |
2014.08.14 |
| 申请号 |
US201214343465 |
申请日期 |
2012.09.07 |
| 申请人 |
Aube Jeffrey;Blagg Brian Scott Jonathan;Frankowski Kevin John;Frick David Norman;Li Kelin;Schoenen Frank John |
发明人 |
Aube Jeffrey;Blagg Brian Scott Jonathan;Frankowski Kevin John;Frick David Norman;Li Kelin;Schoenen Frank John |
| 分类号 |
C07D277/66;C07D417/14;C12Q1/68;A61K45/06;G01N1/30;G01N33/68;A61K31/428;A61K31/4439 |
主分类号 |
C07D277/66 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
Lawrence KS US |
