INNOVATIVE NANO-ELISA SINGLE TEST FOR THE DETECTION OF HCV, HIV ANTIBODIES AND HBSAG

摘要

The invention represents a novel economic and reliable technique to extend the utilization of conventional elisa protocol for detection of single pathogen to accommodate the capability to detect multiple pathogens (such as HIV, HCV and HBSAG) in a single test with enhanced sensitivity. This was achieved via incorporating a large number of a specific type of anybody or multiple types of antibodies into distinctively designed swellable self-assembled and/or hydrogel nanoparticles followed by binding the antibodies-loaded nanoparticles to the elisa plate.